Be able to name and describe 4 functions of blood.
Know the definition and typical value of the hematocrit.
Be able to name and describe the typical functions of 2 types of leukocytes other than the lymphocytes.
Be able to name and describe the typical functions of 2 types of lymphocytes.
Be able to describe the general structure of hemoglobin “molecules” (four peptide chains of two types with each chain having a heme ring.).
Be able to define hemostasis.
Be able to name 4 processes (mechanisms) involved in hemostasis.
Be able to describe the typical size and shape of platelets.
Be able to list 5 structures (organelles) or compounds typically found in platelets.
Be able to describe three things that can cause platelet activation.
Be able to describe what typically happens during platelet activation.
Be able to describe in some detail how NSAID’s can down regulate normal hemostatic processes.
Be able to define coagulation.
Be able to describe the steps in the coagulation cascade from prothrombin to cross-linked fibrin.
Be able to describe what initiates coagulation via the extrinsic pathway.
Be able to describe what initiates coagulation via the intrinsic pathway.
Be able to state what clotting factor is typically considered the beginning of the common pathway.
Be able to define fibrinolysis and anticoagulation such that the differences between these processes are emphasized.
Be able to name 4 factors (chemicals) involved in fibrinolysis.
Be able to name, describe the mode of action and typical applications of three common anticoagulants.
Be able to explain what citrate can’t be used as an in vivo anticoagulant.
Be able to explain what makes heparin a particularly good anticoagulant to use during cardiopulmonary bypass surgery.
Be able to explain why the anticoagulant effects of coumarins are slow to take effect and slow to reverse.
Be able to describe 4 immune system functions.
Be able to name and describe the typical functions of 2 types of leukocytes other than the lymphocytes (repeated from blood components objectives).
Be able to name and describe the typical functions of 2 types of lymphocytes (repeated from blood components objectives).
Be able to name 4 inflammatory agents.
Be able to describe the general processes involved in specific immunity (including descriptions of antigens and antibodies).
Be able to explain the differences among primary, secondary and passive immunity.
Be able to describe the general nature and function of the compliment system.
Be able to explain how specific immunity explains ABO blood compatibility.