Learning Objectives – Osmolariry, Microcirculation, Lymphatics

BI-374, Spring '06, Dr. C. S. Tritt

Osmolality

Know what the terms isosmotic, hyperosmotic and hyposmotic mean.

Know what the terms isotonic, hypertonic and hypotonic mean (this should be in your biology book).

Know to what the term oncotic refers.

Be able to determine the direction of water transport when it is subject to a combination of hydraulic and osmotic (including oncotic and tonic) pressures.

Microcirculation and Lymphatic System

Be able to describe the purpose of the microcirculation.

Be able to describe the purpose of the lymphatic system.

Be able to name a naturally occurring substance (other than water) in the plasma that moves relatively freely (has a permeability of more than half that of water) across most capillary membranes.

Be able to describe the component and basic structure of the interstitial space.

Be able to describe (Modified 5/14/06 - probably using one or more sketches) the structure of the microcirculation.

Be able to explain how the typical negative tissue pressure is produced and maintained.

Be able to name a naturally occurring substance in the plasma that does not move freely across most capillary membranes.

Know the difference between flow-limited and diffusion-limited transport of solutes to the tissues.

Be able to distinguish between (ordinary) osmotic pressure and oncotic (or colloid osmotic) pressure.

Know the meanings of the terms in the equation expressing the Starling hypothesis and be able to use this equation. This equation may not have been called by name in your book or in lecture. It's the one involving capillary and interstitial hydraulic and oncotic pressures.